AF647 Mouse Anti-human CD8a Antibody（OKT8）
一键复制信息
- 产品描述
- 组成成分
- 注意事项
-
产品概述:
产品名称：AF647 Mouse Anti-human CD8a Antibody (OKT8)
抗体类型：Monoclonal
验证应用：FC
宿主：Mouse
种属反应性：Human
偶联物：AF647
克隆号：OKT8
激发光/发射光：648/664
亚型：Mouse IgG2a, κ产品背景：
The OKT8 monoclonal antibody specifically recognizes CD8 alpha (CD8a or CD8α). CD8a is a ~32-34 kDa type I transmembrane glycoprotein that is encoded by CD8A, which belongs to the immunoglobulin superfamily (IgSF), and is commonly referred to as CD8.
CD8a is expressed by the majority of thymocytes, subpopulations of αβ T cells and γδ T cells, and by subsets of NK cells. Cell surface CD8a is expressed either as a disulfide-linked homodimer (CD8αα) or as a heterodimer (CD8αβ) when disulfide-bonded to a CD8 beta chain (CD8b or CD8β). CD8-positive αβ T cells coexpress both CD8αα homodimers and CD8αβ heterodimers whereas some γδ T cells and NK cells express CD8αα homodimers. CD8 plays important roles in T cell activation and selection. The extracellular IgSF domain of CD8α binds to a non-polymorphic determinant on HLA class I molecules (α3 domain) and enables CD8 to function as a coreceptor with MHC class I-restricted TCR during T cell recognition of antigen. The cytoplasmic domain of CD8α associates with Lck, a Src family protein tyrosine kinase that is involved in intracellular signaling. The OKT8 antibody reportedly crossreacts with CD8a expressed by leucocytes from some non-human primate (NHP) species.
Other Names: T8, Leu2
Excitation Laser: Red laser (633-nm). -
产品组成：
货号/规格 组分名称 体积 26-1008-12 25T AF647 Mouse Anti-human CD8a Antibody (OKT8) 125 μL 26-1008-15 100T AF647 Mouse Anti-human CD8a Antibody (OKT8) 500 μL 保存：2-8℃避光保存。冰袋运输。
关键词
产品推荐
AF647 Mouse Anti-human CD123 Antibody （6H6）
货号：26-1123-1
应用：FC
种属反应性：Human
宿主种属：Mouse
AF647 Rat Anti-mouse CD4 Antibody（GK1.5）
货号：26-2004-1
应用：FC
种属反应性：Mouse
宿主种属：Rat
AF647 Rat Anti-mouse PD-L1 Antibody（10F.9G2）
货号：26-2274-1
应用：FC
种属反应性：Mouse
宿主种属：Rat
AF647 Anti-GFP Antibody（RGF-01）
货号：26-7003-1
应用：FC
种属反应性：GFP and virus
宿主种属：Rabbit
AF647 Rat Anti-mouse F4/80 Antibody（A3-1）
货号：26-27001-1
应用：FC
种属反应性：Mouse
宿主种属：Rat
提交您的留言
如果您对我们的产品感兴趣，请留下您的电子邮件地址，我们将尽快与您联系。谢谢！
小红书
抖音
公众号
积分商城
广州市黄埔区瑞和路39号G5座321-332号
客服二维码
