InVivo Prime Pro Anti-Mouse PD-1 Recombinant mAb [RMP1-14]
应用:
In vivo
种属反应性:
Mouse
宿主种属:
Rat
- 产品描述
- 组成成分
- 注意事项
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Product overview:
产品名称: InVivo Prime Pro Anti-Mouse PD-1 Recombinant mAb [RMP1-14]
抗体类型: Monoclonal
application: in vivo
宿主: Rat
反应性: Mouse
克隆编号: 10F.9G2
同型: Rat IgG2b.Background of the target:
PD-1 (also known as CD279) is an immune checkpoint receptor that negatively regulates immune responses and helps
maintain self-tolerance. Multiple immune cells express PD-1, including T cells, B cells, macrophages and dendritic cells. Binding of PD-1 to PD-L1/PD-L2 will lead to the inhibition of T-cell activation and function. Immunotherapy strategies that inhibit the binding of PD-1 and PD-L1 have shown great efficacy in cancer treatment.
Location: Cell membrane
NCBI Gene ID: 18566
SwissProt: Q02242
Alternate Names: Programmed Death-1, Ly101, Pdc1, CD279
Properties
Form Liquid Formulation The antibody is formulated in PBS (pH 7.2) without carrier protein and preservatives. Sterile by 0.22 µm filtration. Purity >95%. Determined by SDS-PAGE. Endotoxin < 0.001 EU/μg. Determined by the LAL assay. Shipping 2-8°C. Storage The product should be stored under sterile conditions at 2-8°C. 应用 dilutions
Flow Cytometry 0.2 μg/mL 应用 data
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Storage: Store at 2–8°C, protected from light. Transport with ice packs.
关键词
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